Consultant Chief Scientific Officer
Sean is an Australian born, formerly Brisbane based, scientific entrepreneur who currently resides in the United States and is the Managing Director of Cleo Life Sciences, a CMC consulting firm. His business leadership skills include venture initiation, market planning, corporate development, due diligence (licensing, M&A, integration), and strategic partnerships.
He is a contributor and leader in the CMC development of 4 commercial drugs, including late-stage development and NDA support to Kyprolis® (carfilzomib, Onyx Pharmaceuticals), Vibativ® (telavancin, Theravance), OxbrytaTM (voxelotor, Global Blood Therapeutics), and early development CMC support to Yupleri® (revefenacin, Theravance). He has supported CMC aspects of over 30 clinical staged IND/IMPD drug candidates, including 6 currently in registration trials across oncology, COVID-19, RSV, auto-immune, and NASH indications.
Sean’s technology leadership expertise includes CMC, strategic planning and project execution, manufacturing process and supply chain development (drug substance and drug product), technology transfer, scale-up and cGMP operations, validation, commercialization and CMC regulatory affairs with global health authorities. He has strong scientific and engineering research skills applied across oral, injectable, and inhaled dosage forms. Sean contributed to inhaled drug development at Theravance (Innoviva, Inc.) during the Strategic Alliance with GSK, now with a commercial DPI portfolio including Breo®, Anoro®, and Trelegy®. At DuPont, Sean contributed to particle engineering and device technologies for DPI and Dymel propellant MDI products.
Sean was VP Head of Technical Operations at Tobira Therapeutics, and at Onyx Pharmaceuticals, Head of Pharmaceutical Sciences at Theravance, and held roles of increasing responsibilities at DuPont, and CSIRO. He is currently Co-founder and Managing Director of Cleo Life Sciences. Sean holds a PhD degree in Chemical Engineering from the University of Queensland and an MBA from UC Berkeley.